22 abril 2015

CIRCULATION. Vascular Medicine. Segmental Aortic Stiffening Contributes to Experimental Abdominal Aortic Aneurysm Development

Uwe Raaz, MD; Alexander M. Zöllner, MS; Isabel N. Schellinger; Ryuji Toh, MD, PhD; Futoshi Nakagami, MD, PhD; Moritz Brandt, MD; Fabian C. Emrich, MD; Yosuke Kayama, MD, PhD; Suzanne Eken, MD; Matti Adam, MD; Lars Maegdefessel, MD, PhD; Thomas Hertel, MD; Alicia Deng; Ann Jagger, PhD; Michael Buerke, MD; Ronald L. Dalman, MD; Joshua M. Spin, MD, PhD; Ellen Kuhl, PhD; Philip S. Tsao, PhD

Background: Stiffening of the aortic wall is a phenomenon consistently observed in age and in abdominal aortic aneurysm (AAA). However, its role in AAA pathophysiology is largely undefined.

01 agosto 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. New Techniques. Multimodality Intra-Arterial Imaging Assessment of the Vascular Trauma Induced by Balloon-Based and Nonballoon-Based Renal Denervation Systems

Antonios Karanasos, MD, PhD, Nicolas Van Mieghem, MD, PhD, Martin W. Bergmann, MD, PhD, Eline Hartman, MD, Jurgen Ligthart, BSc, Elco van der Heide, MSc, Christian-H. Heeger, MD, Mohamed Ouhlous, MD, PhD, Felix Zijlstra, MD, PhD, Evelyn Regar, MD, PhD and Joost Daemen, MD, PhD

Background: Renal denervation is a new treatment considered for several possible indications. As new systems are introduced, the incidence of acute renal artery wall injury with relation to the denervation method is unknown. We investigated the acute repercussion of renal denervation on the renal arteries of patients treated with balloon-based and nonballoon-based denervation systems by quantitative angiography, intravascular ultrasound, and optical coherence tomography (OCT).

01 agosto 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. New Techniques. Selective Proximal Renal Denervation Guided by Autonomic Responses Evoked via High-Frequency Stimulation in a Preclinical Canine Model

Jiayi Lu, MM*, Zhenglong Wang, PhD*, Tingquan Zhou, PhD, Shaojie Chen, PhD, Weijie Chen, MM, Huaan Du, PhD, Zhen Tan, MM, Hanxuan Yang, MM, Xinyu Hu, MM, Chang Liu, MM, Zhiyu Ling, PhD, Zengzhang Liu, MD, Bernhard Zrenner, MD, Kamsang Woo, MD and Yuehui Yin, MD

Background: Electric stimulation has been proved to be available to monitor the efficacy of renal denervation (RDN). This study was to evaluate the effectiveness of high-frequency stimulation (HFS)–guided proximal RDN.

01 agosto 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Peripheral Vascular Disease. Vascular Flow Reserve Immediately After Infrapopliteal Intervention as a Predictor of Wound Healing in Patients With Foot Tissue Loss

Masashi Fukunaga, MD, Kenichi Fujii, MD, Daizo Kawasaki, MD, Machiko Nishimura, MD, Tetsuo Horimatsu, MD, Ten Saita, MD, Kojiro Miki, MD, Hiroto Tamaru, MD, Takahiro Imanaka, MD, Yoshiro Naito, MD and Tohru Masuyama, MD

Background: The purpose of this study was to verify whether the concept of coronary blood flow reserve can be applied to patients with critical limb ischemia who are undergoing endovascular treatment (EVT) for isolated infrapopliteal lesions.

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. A Prospective, Multicenter Study of a Novel Mesh-Covered Carotid Stent. The CGuard CARENET Trial (Carotid Embolic Protection Using MicroNet)

Joachim Schofer, MD∗; Piotr Musiałek, MD, DPhil†; Klaudija Bijuklic, MD∗; Ralf Kolvenbach, MD‡; Mariusz Trystula, MD†; Zbigniew Siudak, MD†; Horst Sievert, MD‖

Objectives: This study sought to evaluate the feasibility of the CGuard Carotid Embolic Protective Stent system—a novel thin strut nitinol stent combined with a polyethylene terephthalate mesh covering designed to prevent embolic events from the target lesion in the treatment of carotid artery lesions in consecutive patients suitable for carotid artery stenting.

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. The Effect of Post-Exercise Ankle-Brachial Index on Lower Extremity Revascularization

Tarek A. Hammad, MD∗; Jason A. Strefling, DO†; Paul R. Zellers, DO†; Grant W. Reed, MD‡; Sridhar Venkatachalam, MD∗; Ashley M. Lowry, MS§; Heather L. Gornik, MD‡; John R. Bartholomew, MD‡; Eugene H. Blackstone, MD§; Mehdi H. Shishehbor, DO, MPH, PhD‡

Objectives: The purpose of this study was to investigate the effect of post-exercise ankle-brachial index (ABI) on the incidence of lower extremity (LE) revascularization, cardiovascular outcomes, and all-cause mortality in patients with normal and abnormal resting ABI.

01 mayo 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Hospital Variation in Carotid Stenting Outcomes

Beau M. Hawkins, MD∗; Kevin F. Kennedy, MS†; Herbert D. Aronow, MD, MPH‡; Louis L. Nguyen, MD, MBA, MPH§; Christopher J. White, MD‖; Kenneth Rosenfield, MD¶; Sharon-Lise T. Normand, PhD#; John A. Spertus, MD, MPH†; Robert W. Yeh, MD, MSc¶

Objectives: The aim of this study was to examine variation in outcomes for patients receiving carotid artery stenting (CAS) across a sample of U.S. hospitals and assess the extent to which this variation was attributable to differences in case mix and procedural volume.

01 junio 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Atrial Remodeling Following Catheter-Based Renal Denervation Occurs in a Blood Pressure– and Heart Rate–Independent Manner CME

Stephan H. Schirmer, MD, PhD; Marwa M.Y.A. Sayed, MD; Jan-Christian Reil, MD; Daniel Lavall, MD; Christian Ukena, MD; Dominik Linz, MD PhD; Felix Mahfoud, MD; Michael Böhm, MD

Objectives: This study sought to investigate left atrial (LA) remodeling in relation to blood pressure (BP) and heart rate (HR) after renal sympathetic denervation (RDN).

01 junio 2015

JACC: CARDIOVASCULAR INTERVENTIONS. 6-Month Outcomes in Patients With Implantable Cardioverter-Defibrillators Undergoing Renal Sympathetic Denervation for the Treatment of Refractory Ventricular Arrhythmias

Luciana V. Armaganijan, MD, MHS∗; Rodolfo Staico, MD, PhD∗; Dalmo A.R. Moreira, MD, PhD∗; Renato D. Lopes, MD, PhD†; Paulo T.J. Medeiros, MD, PhD∗; Ricardo Habib, MD∗; Jônatas Melo Neto, MD∗; Marcelo Katz, MD, PhD, MHS‡; Dikran Armaganijan, MD, PhD∗; Amanda G.M.R. Sousa, MD, PhD∗; Felix Mahfoud, MD§; Alexandre Abizaid, MD, PhD∗

Objectives: This study aimed to assess 6-month outcomes in patients with implantable cardioverter-defibrillators (ICDs) undergoing renal sympathetic denervation (RSD) for refractory ventricular arrhythmias (VAs).

01 julio 2015

JACC: CARDIOVASCULAR INTERVENTIONS. 1-Year Results of the ZEPHYR Registry (Zilver PTX for the Femoral Artery and Proximal Popliteal Artery)

Osamu Iida, MD∗; Mitsuyoshi Takahara, MD, PhD†; Yoshimitsu Soga, MD§; Masatsugu Nakano, MD, PhD‖; Yasutaka Yamauchi, MD, PhD¶; Kan Zen, MD, PhD#; Daizo Kawasaki, MD, PhD∗∗; Shinsuke Nanto, MD, PhD††; Hiroyoshi Yokoi, MD‡‡; Masaaki Uematsu, MD, PhD∗

Objectives: This study sought to assess the rate and predictors of 1-year restenosis after drug-eluting stent implantation for femoropopliteal (FP) lesions in patients with peripheral arterial disease.

01 julio 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Impact of Paclitaxel Dose on Tissue Pharmacokinetics and Vascular Healing. A Comparative Drug-Coated Balloon Study in the Familial Hypercholesterolemic Swine Model of Superficial Femoral In-Stent Restenosis

Carlos A. Gongora, MD∗; Masahiko Shibuya, MD∗; Jeffrey D. Wessler, MD†; Jenn McGregor, BS∗; Armando Tellez, MD‡; Yanping Cheng, MD∗; Gerard B. Conditt, RCIS∗; Greg L. Kaluza, MD, PhD∗; Juan F. Granada, MD∗

Objectives: This study sought to compare the effect of paclitaxel-coated balloon (PCB) concentration on tissue levels and vascular healing using 3 different PCB technologies (In.Pact Pacific = 3 μg/mm2, Lutonix = 2 μg/mm2 and Ranger = 2 μg/mm2) in the experimental setting.

01 abril 2015

EUROPEAN JOURNAL OF VASCULAR & ENDOVASCULAR SURGERY. Short-term Outcome of Spinal Cord Ischemia after Endovascular Repair of Thoracoabdominal Aortic Aneurysms

N.V. Dias, B. Sonesson, T. Kristmundsson, H. Holm, T. Resch

Objective: To analyze the incidence and short-term outcome of SCI after endovascular repair of thoracoabdominal aneurysms (eTAAA).

01 abril 2015

EUROPEAN JOURNAL OF VASCULAR & ENDOVASCULAR SURGERY. Intra-operative Cone Beam Computed Tomography can Help Avoid Reinterventions and Reduce CT Follow up after Infrarenal EVAR

P. Törnqvist, N. Dias, B. Sonesson, T. Kristmundsson, T. Resch

Objective/Background: Re-interventions after endovascular abdominal aortic aneurysm repair (EVAR) are common and therefore a strict imaging follow up protocol is required. The purpose of this study was to evaluate whether cone beam computed tomography (CBCT) can detect intra-operative complications and to compare this with angiography and the 1 month CT follow up (computed tomography angiography [CTA]).

01 abril 2015

EUROPEAN JOURNAL OF VASCULAR & ENDOVASCULAR SURGERY. The Role of Branch Vessels in Aortic Type B Dissection: An in vitro Study

H.T.C. Veger, J.J.M. Westenberg, M.J.T. Visser

Objectives: In acute type B aortic dissection (ABAD) a patent false lumen portends a poor outcome. Patent branch vessels originating from the false lumen in a type B aortic dissection are assumed to contribute to persistent blood flow and patent false lumen. Therefore, the morphologic changes of the false lumen generated by different outflow rates in an in vitro model were investigated.

01 abril 2015

EUROPEAN JOURNAL OF VASCULAR & ENDOVASCULAR SURGERY. Differential Impact of Bypass Surgery and Angioplasty on Angiosome-Targeted Infrapopliteal Revascularization

K. Spillerova, F. Biancari, A. Leppäniemi, A. Albäck, M. Söderström, M. Venermo

Objective: The aim of this study was to evaluate the impact of angiosome targeted revascularization according to the revascularization method.