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ESTUDIOS


13 noviembre 2014

CIRCULATION. Epidemiology and Prevention. Mortality From Thoracic Aortic Diseases and Associations With Cardiovascular Risk Factors

David Sidloff, MRCS, MBBS, BSc (Hon); Edward Choke, PhD, FRCS, MBBS; Philip Stather, MRCS, MBChB, MRCS; Matthew Bown, MD, FRCS, PGCert (Bioinformatics); John Thompson, PhD; Robert Sayers, MBChB (Hons), FRCS (Ed), FRCS (Eng), MD

Background: Temporal trends in mortality from thoracic aortic disease are unclear. This study examined trends in mortality from thoracic aortic aneurysm (TAA) and aortic dissection (AD) with the aim of identifying associations with trends in established cardiovascular risk factors.

03 diciembre 2014

CIRCULATION. Vascular Medicine. Drug-Coated Balloon Versus Standard Percutaneous Transluminal Angioplasty for the Treatment of Superficial Femoral and Popliteal Peripheral Artery Disease. 12-Month Results From the IN.PACT SFA Randomized Trial

Gunnar Tepe, MD; John Laird, MD; Peter Schneider, MD; Marianne Brodmann, MD; Prakash Krishnan, MD; Antonio Micari, MD; Christopher Metzger, MD; Dierk Scheinert, MD; Thomas Zeller, MD; David J. Cohen, MD, MSc; David B. Snead, PhD; Beaux Alexander, MBA; Mario Landini, MS; Michael R. Jaff, DO; for the IN.PACT SFA Trial Investigators*

Background: Drug-coated balloons (DCBs) have shown promise in improving the outcomes for patients with peripheral artery disease. We compared a paclitaxel-coated balloon with percutaneous transluminal angioplasty (PTA) for the treatment of symptomatic superficial femoral and popliteal artery disease.

19 septiembre 2014

CIRCULATION. Why Patients Know More About Cars Than Peripheral Artery Disease

Michael R. Jaff, DO, FACC

Americans who are interested in purchasing a motor vehicle often investigate automobile manufacturers, car models, and even competitive pricing using the World Wide Web. When one uses an Internet search engine to investigate Toyota, the largest automobile manufacturer in the world, there are >93 000 000 results. Virtually every possible question one would have about a Toyota vehicle is discoverable before ever visiting a local Toyota dealership.

01 agosto 2015

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Peripheral Vascular Disease. Ultrasound-Assisted Versus Conventional Catheter-Directed Thrombolysis for Acute Iliofemoral Deep Vein Thrombosis

Rolf P. Engelberger, MD, David Spirk, MD, Torsten Willenberg, MD, Adriano Alatri, MD, Dai-Do Do, MD, Iris Baumgartner, MD and Nils Kucher, MD

Background: For patients with acute iliofemoral deep vein thrombosis, it remains unclear whether the addition of intravascular high-frequency, low-power ultrasound energy facilitates the resolution of thrombosis during catheter-directed thrombolysis.

01 febrero 2016

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Peripheral Vascular Disease. Percutaneous Transluminal Angioplasty and Drug-Eluting Stents for Infrapopliteal Lesions in Critical Limb Ischemia (PADI) Trial

Marlon I. Spreen, MD, Jasper M. Martens, MD, Bettina E. Hansen, PhD, Bob Knippenberg, MD, PhD, Elke Verhey, Lukas C. van Dijk, MD, PhD, Jean-Paul P.M. de Vries, MD, PhD, Jan-Albert Vos, MD, PhD, Gert Jan de Borst, MD, PhD, Evert-Jan P.A. Vonken, MD, PhD, Jan J. Wever, MD, PhD, Randolph G. Statius van Eps, MD, PhD, Willem P.Th.M. Mali, MD, PhD and Hans van Overhagen, MD, PhD

Background: Endovascular infrapopliteal treatment of patients with critical limb ischemia using percutaneous transluminal angioplasty (PTA) and bail-out bare metal stenting (BMS) is hampered by restenosis. In interventional cardiology, drug-eluting stents (DES) have shown better patency rates and are standard practice nowadays. An investigator-initiated, multicenter, randomized trial was conducted to assess whether DES also improve patency and clinical outcome of infrapopliteal lesions.

01 febrero 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Zilver PTX Post-Market Surveillance Study of Paclitaxel-Eluting Stents for Treating Femoropopliteal Artery Disease in Japan. 12-Month Results

Hiroyoshi Yokoi, MDa; Takao Ohki, MD, PhDb; Kimihiko Kichikawa, MDc; Masato Nakamura, MD, PhDd; Kimihiro Komori, MD, PhDe; Shinsuke Nanto, MD, PhDf; Erin E. O’Leary, PhDg; Aaron E. Lottes, PhDg; Scott A. Snyder, PhDg; Michael D. Dake, MDh

Objectives: This multicenter, prospective, post-market surveillance study in Japan evaluates the paclitaxel-coated Zilver PTX stent in real-world patients with complex lesions.

01 enero 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Randomized Controlled Study of Excimer Laser Atherectomy for Treatment of Femoropopliteal In-Stent Restenosis. Initial Results From the EXCITE ISR Trial (EXCImer Laser Randomized Controlled Study for Treatment of FemoropopliTEal In-Stent Restenosis)

Eric J. Dippel, MD∗; Prakash Makam, MD†; Richard Kovach, MD‡; Jon C. George, MD‡; Raghotham Patlola, MD§; D. Christopher Metzger, MD‖; Carlos Mena-Hurtado, MD¶; Robert Beasley, MD#; Peter Soukas, MD∗∗; Pedro J. Colon-Hernandez, MD††; Matthew A. Stark, PhD‡‡; Craig Walker, MD§§

Objectives: The purpose of this study was to evaluate the safety and efficacy of excimer laser atherectomy (ELA) with adjunctive percutaneous transluminal angioplasty (PTA) versus PTA alone for treating patients with chronic peripheral artery disease with femoropopliteal bare nitinol in-stent restenosis (ISR).

01 enero 2016

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. Time-course of vascular dysfunction of brachial artery after transradial access for coronary angiography

Jerson Munoz-Mendoza MD1,*, Abhijit Ghatak MD2, Veronica Pinto Miranda MD3, Shaka Bahadu MD3, Eduardo De Marchena MD2, Alexandre C. Ferreira MD2,4 andCesar E. Mendoza MD4

Background: Prior studies have demonstrated endothelial and smooth muscle brachial artery dysfunction after transradial cardiac catheterization for diagnostic coronary angiography. The duration of this vascular dysfunction is unknown.

01 enero 2016

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. Outcomes of One straight-line flow with and without pedal arch in patients with critical limb ischemia

Akihiro Higashimori MD1,*, Osamu Iida MD2, Yasutaka Yamauchi MD3, Daizo Kawasaki MD4, Masato Nakamura MD, PhD5, Yoshimitsu Soga MD6, Kan Zen MD7, Yoshiaki Yokoi MD, PhD, FSCAI, FJCC1 andon behalf of the OLIVE Investigators

Objectives: This study aimed to compare the outcomes of revascularization strategies for patients with critical limb ischemia (CLI) whereby single vessel run off to the foot was established with or without flow into a patent pedal arch.

08 septiembre 2015

CIRCULATION. Epidemiology and Prevention. Population-Based Study of Incidence, Risk Factors, Outcome, and Prognosis of Ischemic Peripheral Arterial Events

Dominic P.J. Howard, DPhil; Amitava Banerjee, DPhil; Jack F. Fairhead, MA; Linda Hands, FRCS; Louise E. Silver, DPhil; Peter M. Rothwell, FMedSci; on behalf of the Oxford Vascular Study

Background: There are few published data on the incidence and long-term outcomes of critical limb ischemia, acute limb ischemia, or acute visceral ischemia with which to inform health service planning, to monitor prevention, and to enable risk prediction.

11 septiembre 2015

CIRCULATION. Health Services and Outcomes Research. The Contemporary Safety and Effectiveness of Lower Extremity Bypass Surgery and Peripheral Endovascular Interventions in the Treatment of Symptomatic Peripheral Arterial Disease

Thomas T. Tsai, MD, MSc; Thomas F. Rehring, MD; R. Kevin Rogers, MD, MS; Susan M. Shetterly, MS; Nicole M. Wagner, MS; Rajan Gupta, MD; Omid Jazaeri, MD; Nasim Hedayati, MD; W. Schuyler Jones, MD; Manesh R. Patel, MD; P. Michael Ho, MD, PhD; Alan S. Go, MD; David J. Magid, MD, MPH

Background: Treatment for symptomatic peripheral artery disease includes lower extremity bypass surgery (LEB) and peripheral endovascular interventions (PVIs); however, limited comparative effectiveness data exist between the 2 therapies. We assessed the safety and effectiveness of LEB and PVI in patients with symptomatic claudication and critical limb ischemia.

01 enero 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. C-reactive protein predicts aortic aneurysmal disease progression after endovascular repair

Joaquin De Haro, Silvia Bleda, Francisco Acin

Objectives: This study aims to investigate the prognostic significance of the rate of variation of C-reactive protein (CRP) levels as a predictor of aneurysmal sac and neck expansion and, therefore, of aneurysm disease progression, in patients undergoing endovascular aneurysm repair (EVAR) in the absence of endoleaks.

01 diciembre 2014

JACC: CARDIOVASCULAR INTERVENTIONS. Two-Year Life Expectancy in Patients With Critical Limb Ischemia

Yoshimitsu Soga, MD∗; Osamu Iida, MD†; Mitsuyoshi Takahaera, MD‡; Keisuke Hirano, MD§; Kenji Suzuki, MD‖; Daizo Kawasaki, MD¶; Yusuke Miyashita, MD#; Taketsugu Tsuchiya, MD∗∗

Objectives: This study sought to estimate the 2-year life expectancy (2YLE) (estimated survival rate >50% at 2 years) in patients with critical limb ischemia (CLI) using the risk score based on predictors of all-cause mortality within 2 years.

01 julio 2014

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Personalized Approach to Revascularization of Critical Limb Ischemia

Mehdi H. Shishehbor, DO, PhD, MPH and Grant W. Reed, MD

Critical limb ischemia (CLI) is a complex disease process that often occurs alongside numerous comorbidities, and as such requires a personalized, multidisciplinary treatment approach in every patient. Patient outcomes are generally poor and there remains a lack of consensus on the optimal revascularization strategy in individuals with CLI.

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