01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Stent Repair for Complex Coarctation of Aorta

José Suárez de Lezo, MD, PhD∗; Miguel Romero, MD, PhD∗; Manuel Pan, MD, PhD∗; Javier Suárez de Lezo, MD, PhD∗; José Segura, MD, PhD∗; Soledad Ojeda, MD, PhD∗; Djordje Pavlovic, MD, PhD∗; Francisco Mazuelos, MD, PhD∗; José López Aguilera, MD∗; Simona Espejo Perez, MD†

Objectives: This study sought to determine whether several anatomic or evolving characteristics of the coarctation may create challenging conditions for treatment.

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. A Prospective, Single-Arm, Multicenter Trial of Ultrasound-Facilitated, Catheter-Directed, Low-Dose Fibrinolysis for Acute Massive and Submassive Pulmonary Embolism

Gregory Piazza, MD, MS1; Benjamin Hohlfelder, PharmD1; Michael R. Jaff, DO2; Kenneth Ouriel, MD3; Tod C. Engelhardt, MD4; Keith M. Sterling, MD5; Noah J. Jones, MD6; John C. Gurley, MD7; Rohit Bhatheja, MD8; Robert J. Kennedy, MD9; Nilesh Goswami, MD10; Kannan Natarajan, MD11; John Rundback, MD12; Immad R. Sadiq, MD13; Stephen K. Liu, MD14; Narinder Bhalla, MD15; M. Laiq Raja, MD16; Barry S. Weinstock, MD17; Jacob Cynamon, MD18; Fakhir F. Elmasri, MD19; Mark J. Garcia, MD20; Mark Kumar, MD21; Juan Ayerdi, MD22; Peter Soukas, MD23; William Kuo, MD24; Ping-Yu Liu, PhD25; Samuel Z. Goldhaber, MD2

Objectives: This study conducted a prospective, single-arm, multicenter trial to evaluate the safety and efficacy of ultrasound-facilitated, catheter-directed, low-dose fibrinolysis, using the EkoSonic Endovascular System (EKOS, Bothell, Washington).

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Noninvasive Discrimination of Coronary Chronic Total Occlusion and Subtotal Occlusion by Coronary Computed Tomography Angiography

Jin-Ho Choi, MD, PhD∗; Eun-Kyoung Kim, MD∗; Sung Mok Kim, MD, PhD‡; Hyungyoon Kim, MD∗; Young Bin Song, MD, PhD∗; Joo-Yong Hahn, MD, PhD∗; Seung Hyuk Choi, MD, PhD∗; Hyeon-Cheol Gwon, MD, PhD∗; Sang-Hoon Lee, MD, PhD∗; Yeon Hyeon Choe, MD, PhD‡; Jae K. Oh, MD∗

Objectives: The aim of this study was to investigate whether noninvasive discrimination of chronic total occlusion (CTO), a complete interruption of coronary artery flow, and subtotal occlusion (STO), a functional total occlusion, is feasible using coronary computed tomography angiography (CTA).

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Final 5-Year Follow-Up of a Randomized Controlled Trial of Everolimus- and Paclitaxel-Eluting Stents for Coronary Revascularization in Daily Practice. The COMPARE Trial (A Trial of Everolimus-Eluting Stents and Paclitaxel Stents for Coronary Revascularization in Daily Practice)

Pieter C. Smits, MD, PhD; Georgios J. Vlachojannis, MD, PhD; Eugene Patrick McFadden, MD; Kees-Jan Royaards, MD; Jochem Wassing, MD; Kaiyum Sheik Joesoef, MD; Carlos van Mieghem, MD, PhD; Martin van de Ent, MD, PhD

Objectives: This study sought to report the 5-year outcomes of everolimus-eluting stents (EES) and paclitaxel-eluting stents (PES) in an all-comers population undergoing percutaneous coronary intervention (PCI).

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. A Combined Optical Coherence Tomography and Intravascular Ultrasound Study on Plaque Rupture, Plaque Erosion, and Calcified Nodule in Patients With ST-Segment Elevation Myocardial Infarction

Takumi Higuma, MD, PhD∗; Tsunenari Soeda, MD, PhD†; Naoki Abe, MD, PhD∗; Masahiro Yamada, MD, PhD∗; Hiroaki Yokoyama, MD, PhD∗; Shuji Shibutani, MD, PhD∗; Rocco Vergallo, MD†; Yoshiyasu Minami, MD, PhD†; Daniel S. Ong, MD†; Hang Lee, PhD‡; Ken Okumura, MD, PhD∗; Ik-Kyung Jang, MD, PhD†

Objectives: This study sought to evaluate the incidence of plaque rupture (PR), plaque erosion (PE), and calcified nodule (CN) using optical coherence tomography (OCT) in patients with ST-segment elevation myocardial infarction (STEMI); to compare detailed morphologic plaque characteristics of PR, PE, and CN with optical coherence tomography and intravascular ultrasound; and to compare the post-procedure outcomes among PR, PE, and CN.

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Incidence and Clinical Impact of Stent Fracture After PROMUS Element Platinum Chromium Everolimus-Eluting Stent Implantation

Shoichi Kuramitsu, MD∗; Takashi Hiromasa, MD∗; Soichiro Enomoto, MD†; Tomohiro Shinozaki, MPH‡; Masashi Iwabuchi, MD§; Toru Mazaki, MD∗; Takenori Domei, MD∗; Kyohei Yamaji, MD∗; Yoshimitsu Soga, MD∗; Makoto Hyodo, MD∗; Shinichi Shirai, MD∗; Kenji Ando, MD∗

Objectives: This study sought to assess the incidence and clinical impact of stent fracture (SF) after the PROMUS Element platinum-chromium everolimus-eluting stent (PtCr-EES).

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Effect of Vascular Access Site Choice on Radiation Exposure During Coronary Angiography. The REVERE Trial (Randomized Evaluation of Vascular Entry Site and Radiation Exposure)

Samir B. Pancholy, MD∗; Pankaj Joshi, MD†; Sanjay Shah, MD, DM‡; Sunil V. Rao, MD§; Olivier F. Bertrand, MD, PhD‖; Tejas M. Patel, MD, DM¶

Objectives: This study sought to perform a randomized noninferiority trial of radiation exposure during cardiac catheterization comparing femoral access (FA) with left radial access (LRA) and right radial access (RRA).

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Invasive Cardiologists Are Exposed to Greater Left Sided Cranial Radiation. The BRAIN Study (Brain Radiation Exposure and Attenuation During Invasive Cardiology Procedures)

Ryan R. Reeves, MD; Lawrence Ang, MD; John Bahadorani, MD; Jesse Naghi, MD; Arturo Dominguez, MD; Vachaspathi Palakodeti, MD; Sotirios Tsimikas, MD; Mitul P. Patel, MD; Ehtisham Mahmud, MD

Objectives: This study sought to determine radiation exposure across the cranium of cardiologists and the protective ability of a nonlead, XPF (barium sulfate/bismuth oxide) layered cap (BLOXR, Salt Lake City, Utah) during fluoroscopically guided, invasive cardiovascular (CV) procedures.

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Health Status After Transcatheter or Surgical Aortic Valve Replacement in Patients With Severe Aortic Stenosis at Increased Surgical Risk

Suzanne V. Arnold, MD, MHA∗; Matthew R. Reynolds, MD, MSc‡; Kaijun Wang, PhD∗; Elizabeth A. Magnuson, ScD∗; Suzanne J. Baron, MD, MSc∗; Khaja M. Chinnakondepalli, MS∗; Michael J. Reardon, MD§; Peter N. Tadros, MD‖; George L. Zorn, MD‖; Brij Maini, MD¶; Mubashir A. Mumtaz, MD¶; John M. Brown, MD#; Robert M. Kipperman, MD#; David H. Adams, MD∗∗; Jeffrey J. Popma, MD††; David J. Cohen, MD, MSc∗

Objectives: This study sought to compare the health status outcomes for patients treated with either self-expanding transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (AVR).

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Inverse Relationship Between Membranous Septal Length and the Risk of Atrioventricular Block in Patients Undergoing Transcatheter Aortic Valve Implantation

Ashraf Hamdan, MD∗; Victor Guetta, MD∗; Robert Klempfner, MD∗; Eli Konen, MD†; Ehud Raanani, MD‡; Michael Glikson, MD∗; Orly Goitein, MD†; Amit Segev, MD∗; Israel Barbash, MD∗; Paul Fefer, MD∗; Dan Spiegelstein, MD‡; Ilan Goldenberg, MD∗; Ehud Schwammenthal, MD, PhD∗

Objectives: This study sought to examine whether imaging of the atrioventricular (AV) membranous septum (MS) by computed tomography (CT) can be used to identify patient-specific anatomic risk of high-degree AV block and permanent pacemaker (PPM) implantation before transcatheter aortic valve implantation (TAVI) with self-expandable valves.

01 agosto 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Acute Thrombogenicity of a Durable Polymer Everolimus-Eluting Stent Relative to Contemporary Drug-Eluting Stents With Biodegradable Polymer Coatings Assessed Ex Vivo in a Swine Shunt Model

Fumiyuki Otsuka, MD, PhD∗; Qi Cheng, MD∗; Kazuyuki Yahagi, MD∗; Eduardo Acampado, DVM∗; Alexander Sheehy, MS†; Saami K. Yazdani, PhD∗; Kenichi Sakakura, MD∗; Kristina Euller∗; Laura E.L. Perkins, DVM, PhD†; Frank D. Kolodgie, PhD∗; Renu Virmani, MD∗; Michael Joner, MD∗

Objectives: This study sought to evaluate whether the permanent fluoropolymer-coated Xience Xpedition everolimus-eluting stent (Xience-EES) exhibits lower acute thrombogenicity compared with contemporary drug-eluting stents (DES) with biodegradable polymer coatings in an acute swine shunt model.

01 mayo 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Safety and Effectiveness of Everolimus-Eluting Stents in Chronic Total Coronary Occlusion Revascularization. Results From the EXPERT CTO Multicenter Trial (Evaluation of the XIENCE Coronary Stent, Performance, and Technique in Chronic Total Occlusions)

David E. Kandzari, MD∗; Annapoorna S. Kini, MD†; Dimitri Karmpaliotis, MD‡; Jeffrey W. Moses, MD‡; Pradyumna E. Tummala, MD§; J. Aaron Grantham, MD||; Charles Orr, MD¶; William Lombardi, MD#; William J. Nicholson, MD∗∗; Nicholas J. Lembo, MD∗; Jeffrey J. Popma, MD††; Jin Wang, PhD‡‡; Cristina Larracas, MD‡‡; David R. Rutledge, PharmD‡‡

Objectives: This study sought to evaluate procedural and clinical outcomes among patients undergoing chronic total occlusion (CTO) percutaneous coronary intervention (PCI) using contemporary methods and everolimus-eluting stents (EES).

01 mayo 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Clinical, Angiographic, Functional, and Imaging Outcomes 12 Months After Implantation of Drug-Eluting Bioresorbable Vascular Scaffolds in Acute Coronary Syndromes

Tommaso Gori, MD, PhD∗; Eberhard Schulz, MD∗; Ulrich Hink, MD∗; Madeleine Kress∗; Nadja Weiers∗; Melissa Weissner∗; Alexander Jabs, MD∗; Philip Wenzel, MD∗; Davide Capodanno, MD, PhD†; Thomas Münzel, MD∗

Objectives: The purpose of this study was to describe the multimodal outcome 12 months after implantation of coronary bioresorbable scaffolds (BVS) for the treatment of patients with acute coronary syndromes (ACS).

01 mayo 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Biochemical Validation of Patient-Reported Symptom Onset Time in Patients With ST-Segment Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention

Karim D. Mahmoud, MD, PhD∗; Hans L. Hillege, MD, PhD†; Allan S. Jaffe, MD∗; Ryan J. Lennon, MS§; David R. Holmes, Jr., MD∗

Objectives: This study evaluated a biochemical validation of patient-reported symptom onset time in patients with ST-segment elevation myocardial infarction (STEMI).

01 mayo 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Sex-Related Outcomes in Elderly Patients Presenting With Non–ST-Segment Elevation Acute Coronary Syndrome

Marco De Carlo, MD, PhD∗; Nuccia Morici, MD†; Stefano Savonitto, MD‡; Vincenzo Grassia, MD§; Paolo Sbarzaglia, MD‖; Paola Tamburrini, MD¶; Claudio Cavallini, MD‖; Marcello Galvani, MD#; Paolo Ortolani, MD∗∗; Stefano De Servi, MD††; A. Sonia Petronio, MD∗

Objectives: This study sought to investigate sex-related differences in treatment and outcomes in elderly patients with non–ST-segment elevation acute coronary syndromes (NSTEACS).