01 noviembre 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Comparison of Stent Expansion Guided by Optical Coherence Tomography Versus Intravascular Ultrasound. The ILUMIEN II Study (Observational Study of Optical Coherence Tomography [OCT] in Patients Undergoing Fractional Flow Reserve [FFR] and Percutaneous Coronary Intervention)

Akiko Maehara, MD∗,†; Ori Ben-Yehuda, MD∗,†; Ziad Ali, MD∗,†; William Wijns, MD, PhD‡; Hiram G. Bezerra, MD§; Junya Shite, MD‖; Philippe Généreux, MD∗,†,¶; Melissa Nichols, MS†; Paul Jenkins, PhD†; Bernhard Witzenbichler, MD#; Gary S. Mintz, MD†; Gregg W. Stone, MD∗,†

Objectives: The present study sought to determine whether optical coherence tomography (OCT) guidance results in a degree of stent expansion comparable to that with intravascular ultrasound (IVUS) guidance.

01 noviembre 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Relation Between Bioresorbable Scaffold Sizing Using QCA-Dmax and Clinical Outcomes at 1 Year in 1,232 Patients From 3 Study Cohorts (ABSORB Cohort B, ABSORB EXTEND, and ABSORB II)

Yuki Ishibashi, MD, PhD∗; Shimpei Nakatani, MD∗; Yohei Sotomi, MD†; Pannipa Suwannasom, MD∗,†,‡; Maik J. Grundeken, MD†; Hector M. Garcia-Garcia, MD, PhD∗; Antonio L. Bartorelli, MD§; Robert Whitbourn, MD‖; Bernard Chevalier, MD¶; Alexandre Abizaid, MD, PhD#; John A. Ormiston, MB, ChB, PhD∗∗; Richard J. Rapoza, PhD††; Susan Veldhof, RN‡‡; Yoshinobu Onuma, MD, PhD∗; Patrick W. Serruys, MD, PhD§§

Objectives: This study sought to investigate the clinical outcomes based on the assessment of quantitative coronary angiography–maximal lumen diameter (Dmax).

01 noviembre 2015

JACC: CARDIOVASCULAR INTERVENTIONS. A Strategy of Underexpansion and Ad Hoc Post-Dilation of Balloon-Expandable Transcatheter Aortic Valves in Patients at Risk of Annular Injury. Favorable Mid-Term Outcomes

John S. Tan, MBBS∗; Jonathon Leipsic, MD∗; Gidon Perlman, MD∗; Dion Stub, MBBS∗; Danny Dvir, MD∗; Nicolaj C. Hansson, MD†; Bjarne L. Norgaard, MD†; Philipp Blanke, MD∗; Anson Cheung, MD∗; Jian Ye, MD∗; Christopher R. Thompson, MD∗; Robert R. Moss, MBBS∗; Sandra Lauck, PhD∗; David Wood, MD∗; John Webb, MD∗

Objectives: The aim of this study was to evaluate a strategy of intentional underexpansion of excessively oversized balloon-expandable transcatheter heart valves (THVs) in terms of clinical outcomes, valve function, and frame durability at 1 year.

01 noviembre 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Transcatheter Aortic and Mitral Valve-in-Valve Implantation for Failed Surgical Bioprosthetic Valves. An 8-Year Single-Center Experience

Jian Ye, MD∗; Anson Cheung, MD∗; Michael Yamashita, MD∗; David Wood, MD†; Defen Peng, PhD‡; Min Gao, MD, PhD‡; Christopher R. Thompson, MD†; Brad Munt, MD†; Robert R. Moss, MD†; Philipp Blanke, MD§; Jonathon Leipsic, MD§; Danny Dvir, MD†; John G. Webb, MD†

Objectives: We report our 8-year experience in transcatheter aortic and mitral valve-in-valve (VinV) implantation.

01 noviembre 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Incidence, Causes, and Predictors of Early (≤30 Days) and Late Unplanned Hospital Readmissions After Transcatheter Aortic Valve Replacement

Luis Nombela-Franco, MD∗; María del Trigo, MD†; Guillermo Morrison-Polo, MD∗; Gabriela Veiga, MD†; Pilar Jimenez-Quevedo, MD, PhD∗; Omar Abdul-Jawad Altisent, MD†; Francisco Campelo-Parada, MD†; Corina Biagioni, MD∗; Rishi Puri, MBBS, PhD†; Robert DeLarochellière, MD†; Eric Dumont, MD†; Daniel Doyle, MD†; Jean-Michel Paradis, MD†; Alicia Quirós, PhD∗; Carlos Almeria, MD∗; Nieves Gonzalo, MD, PhD∗; Ivan Nuñez-Gil, MD, PhD∗; Pablo Salinas, MD, PhD∗; Siamak Mohammadi, MD†; Javier Escaned, MD, PhD∗; Antonio Fernández-Ortiz, MD, PhD∗; Carlos Macaya, MD, PhD∗; Josep Rodés-Cabau, MD†

Objectives: The aim of this study was to determine the incidence, causes, and predictors of unplanned hospital readmissions after transcatheter aortic valve replacement (TAVR).

01 noviembre 2015

JACC: CARDIOVASCULAR INTERVENTIONS. Severe Neointimal Hyperplasia of Neoplastic Carina Following Bioresorbable Scaffold Implantation Using T-Stenting and Small Protrusion Technique. Insights From Optical Frequency Domain Imaging

Hiroyoshi Kawamoto, MD∗,†; Neil Ruparelia, DPhil∗,†,‡; Filippo Figini, MD∗,†; Azeem Latib, MD∗,†; Antonio Colombo, MD∗,†

A 53-year-old man presenting with stable angina underwent coronary angiography demonstrating a critical true bifurcation lesion (Medina 1,1,1) of the left anterior descending coronary artery (LAD). Following pre-dilation, a 3.5 × 18-mm Absorb (Abbott Vascular, Santa Clara, California) bioresorbable scaffold (BRS) was implanted in the LAD with subsequent 3.5-mm high-pressure noncompliant balloon post-dilation.

01 noviembre 2015

INTERNATIONAL JOURNAL OF CARDIOLOGY. Time-dependent effects of unfractionated heparin in patients with ST-elevation myocardial infarction transferred for primary angioplasty

Teresa Giralt, Xavier Carrillo, Oriol Rodriguez-Leor, Eduard Fernandez-Nofrerias, Ferran Rueda, Jordi Serra-Flores, Josep Maria Viguer, Josepa Mauri, Antoni Curos, Antoni Bayes-Genis

Aims: Initial thrombolysis in myocardial infarction (TIMI) flow and mortality are related in ST-elevation myocardial infarction (STEMI) patients treated with primary angioplasty (PPCI). It is unclear whether early adjunctive treatment with unfractionated heparin (UFH) is beneficial for coronary patency. We investigated the effect of UFH administered before transfer versus in the catheterization laboratory (CathLab) on initial patency of the infarct related artery (IRA) in transferred STEMI patients treated with PPCI.

01 noviembre 2015

INTERNATIONAL JOURNAL OF CARDIOLOGY. Short and long-term mortality in women and men undergoing primary angioplasty: A comprehensive meta-analysis

Chirag Bavishi, Sripal Bangalore, Dipen Patel, Saurav Chatterjee, Vrinda Trivedi, Jacqueline E. Tamis-Holland

Introduction: Women with acute myocardial infarction are treated less aggressively than men and have a higher mortality. It is possible that these sex-related differences in outcome are a result of differences in baseline risk and management.

15 noviembre 2015

INTERNATIONAL JOURNAL OF CARDIOLOGY. Prognostic value of SYNTAX score based on coronary computed tomography angiography

Young Joo Suh, Yoo Jin Hong, Hye-Jeong Lee, Jin Hur, Young Jin Kim, Hye Sun Lee, Sae Rom Hong, Dong Jin Im, Yun Jung Kim, Chul Hwan Park, Tae Hoon Kim, Kyung-Jong Yoo, Byoung Wook Choi

Background: The long-term prognostic value of the computed tomography (CT)-based SYNTAX score has not yet been investigated. The aim of our study was to investigate the prognostic value of the CT-SYNTAX score in predicting major adverse cardiac events (MACEs) in populations who underwent both coronary computed tomography (CCTA) and invasive coronary angiography (ICA), compared with prognostic values of coronary artery disease (CAD) findings on CCTA and the ICA-based SYNTAX score.

15 noviembre 2015

INTERNATIONAL JOURNAL OF CARDIOLOGY. Large platelets but not putative endothelial progenitor cells are associated with low strut coverage after drug-eluting stent implantation

Thomas G. Nührenberg, Min Zhao, Christian Stratz, Michael Amann, Christian M. Valina, Michael Gick, Dietmar Trenk, Harald Binder, Heinz Joachim Büttner, Franz-Josef Neumann

Objectives: This study assessed whether different subsets of circulating endothelial and putative endothelial progenitor cells (CEC and EPC) correlate with stent strut coverage (SSC) using second generation optical coherence tomography (OCT).

15 noviembre 2015

INTERNATIONAL JOURNAL OF CARDIOLOGY. Antiplatelet therapy discontinuation and stent thrombosis after sirolimus-eluting stent implantation: Five-year outcome of the j-Cypher Registry

Mariko Yano, Masahiro Natsuaki1, Takeshi Morimoto, Yoshihisa Nakagawa, Kazuya Kawai, Shunichi Miyazaki, Toshiya Muramatsu, Nobuo Shiode, Masanobu Namura, Takahito Sone, Shigeru Oshima, Hideo Nishikawa, Yoshikazu Hiasa, Yasuhiko Hayashi, Masakiyo Nobuyoshi, Kazuaki Mitsudo, Takeshi Kimura, on behalf of the j-Cypher Registry Investigators

Background: The influence of antiplatelet therapy discontinuation on the incidence of stent thrombosis, especially very late stent thrombosis, after drug-eluting stent implantation has not been yet fully addressed.

15 noviembre 2015

INTERNATIONAL JOURNAL OF CARDIOLOGY. Management of concomitant coronary artery disease in patients undergoing transcatheter aortic valve implantation: The United Kingdom TAVI Registry

Thomas M. Snow, Peter Ludman, Winston Banya, Mark DeBelder, Philip M. MacCarthy, Simon W. Davies, Carlo Di Mario, Neil E. Moat

Background: The management and impact of concomitant coronary artery disease in patients referred for TAVI remains contentious. We describe the prevalence, clinical impact and management of coronary artery disease (CAD) in patients in the United Kingdom TAVI Registry.

15 noviembre 2015

INTERNATIONAL JOURNAL OF CARDIOLOGY. Comparison of Resolute zotarolimus-eluting stents versus everolimus-eluting stents in patients with metabolic syndrome and acute myocardial infarction

Mi Seon Ji1, Myung Ho Jeong, Young Keun Ahn, Sang Hyung Kim, Young Jo Kim, Shung Chull Chae, Taek Jong Hong, In Whan Seong, Jei Keon Chae, Chong Jin Kim, Myeong Chan Cho, Seung-Woon Rha, Jang Ho Bae, Ki Bae Seung, Seung Jung Park, Seung Ho Hur and other Korea Acute Myocardial Infarction Registry Investigators

Background: Despite common use of second-generation drug-eluting stents in treating patients with coronary artery disease, there is lack of data comparing these stents exclusively in patients with acute myocardial infarction (AMI), especially with metabolic syndrome (MetS), which is highly prevalent in AMI and potential to worsen clinical outcomes. The aim of this study was to compare clinical outcomes of everolimus-eluting stent (EES) and Resolute-zotarolimus-eluting stent (R-ZES) in AMI patients with MetS, in terms of stent-related and patient-related outcomes.

15 noviembre 2015

INTERNATIONAL JOURNAL OF CARDIOLOGY. Comparison of instantaneous wave-free ratio (iFR) and fractional flow reserve (FFR) — First real world experience

Tobias Härle, Waldemar Bojara1, Sven Meyer1, Albrecht Elsässer1

Background: The instantaneous wave-free ratio (iFR) is a new adenosine-independent index of coronary stenosis severity. Most published data have been based on off-line analyses of pressure recordings in a core laboratory. We prospectively compared real-time iFR and fractional flow reserve (FFR) measurements.

15 diciembre 2015

INTERNATIONAL JOURNAL OF CARDIOLOGY. Incremental diagnostic accuracy of computed tomography myocardial perfusion imaging over coronary angiography stratified by pre-test probability of coronary artery disease and severity of coronary artery calcification: The CORE320 study

Ravi K. Sharma, Armin Arbab-Zadeh, Satoru Kishi, Marcus Y. Chen, Tiago A. Magalhães, Richard T. George, Marc Dewey, Frank J. Rybicki, Klaus F. Kofoed, Albert de Roos, Swee Yaw Tan, Matthew Matheson, Andrea Vavere, Christopher Cox, Melvin E. Clouse, Julie M. Miller, Jeffery A. Brinker, Andrew E. Arai, Marcelo F. Di Carli, Carlos E. Rochitte, Joao A.C. Lima

Background: Myocardial CT perfusion (CTP) has been validated as an incremental diagnostic predictor over coronary computed tomography angiography (CTA) in assessing hemodynamically significant stenosis.