17 febrero 2016

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Coronary Physiologic Assessment and Imaging. Transcatheter Replacement of Stenotic Aortic Valve Normalizes Cardiac–Coronary Interaction by Restoration of Systolic Coronary Flow Dynamics as Assessed by Wave Intensity Analysis

M. Cristina Rolandi, PhD, Esther M.A. Wiegerinck, MD, Lorena Casadonte, MSc, Ze-Yie Yong, MD, PhD, Karel T. Koch, MD, PhD, Marije Vis, MD, PhD, Jan J. Piek, MD, PhD, Jan Baan Jr, MD, PhD, Jos A.E. Spaan, PhD and Maria Siebes, PhD

Background: Aortic valve stenosis (AS) can cause angina despite unobstructed coronary arteries, which may be related to increased compression of the intramural microcirculation, especially at the subendocardium. We assessed coronary wave intensity and phasic flow velocity patterns to unravel changes in cardiac–coronary interaction because of transcatheter aortic valve implantation (TAVI).

11 enero 2016

CIRCULATION: CARDIOVASCULAR INTERVENTIONS. Cardiac Catheterization. Predictors of Outcome After Alcohol Septal Ablation for Hypertrophic Obstructive Cardiomyopathy. An Echocardiography and Cardiovascular Magnetic Resonance Imaging Study

Minjie Lu, MD, PhD*, Hui Du, MD*, Zhan Gao, MD, Lei Song, MD, Huaibing Cheng, PhD, Yan Zhang, MD, Gang Yin, BS, Xiuyu Chen, PhD, Jian Ling, MD, Yong Jiang, MD, Hao Wang, MD, Jinghui Li, MD, Jinghan Huang, MD, Zuoxiang He, MD, PhD and Shihua Zhao, MD, PhD, FESC

Background: Alcohol septal ablation (ASA) is used for treatment of medically refractory hypertrophic obstructive cardiomyopathy patients with severe left ventricular outflow tract (LVOT) obstruction. The current recommendations restrict the procedure to adults with favorable anatomy and no other coexisting surgically amenable disease. Some patients remain symptomatic with residual LVOT obstruction, thus better patient selection is required.

21 marzo 2016

CIRCULATION. Congenital Heart Disease. Relative Risk Factors for Cardiac Erosion Following Transcatheter Closure of Atrial Septal Defects. A Case–Control Study

Doff B. McElhinney, MD; Michael D. Quartermain, MD; Damien Kenny, MD; Ernerio Alboliras, MD; Zahid Amin, MD

Background: Transcatheter closure of secundum atrial septal defects (ASD) using the Amplatzer septal occluder is generally safe and effective, but erosion into the pericardial space or aorta has been described. Although the absolute risk of this complication is low, there has been no assessment of relative risk factors.

18 marzo 2016

CIRCULATION. Interventional Cardiology. Transcatheter Tricuspid Valve-in-Valve Implantation for the Treatment of Dysfunctional Surgical Bioprosthetic Valves. An International, Multicenter Registry Study

Doff B. McElhinney, MD; Allison K. Cabalka, MD; Jamil A. Aboulhosn, MD; Andreas Eicken, MD; Younes Boudjemline, MD; Stephan Schubert, MD; Dominique Himbert, MD; Jeremy D. Asnes, MD; Stefano Salizzoni, MD; Martin L. Bocks, MD; John P. Cheatham, MD; Tarek S. Momenah, MD; Dennis W. Kim, MD; Dietmar Schranz, MD; Jeffery Meadows, MD; John D.R. Thomson, MD; Bryan H. Goldstein, MD; Ivory Crittendon III, MD; Thomas E. Fagan, MD; John G. Webb, MD; Eric Horlick, MD; Jeffrey W. Delaney, MD; Thomas K. Jones, MD; Shabana Shahanavaz, MD; Carolina Moretti, MD; Michael R. Hainstock, MD; Damien P. Kenny, MD; Felix Berger, MD; Charanjit S. Rihal, MD; Danny Dvir, MD; for the Valve-in-Valve International Database (VIVID) Registry

Background: Off-label use of transcatheter aortic and pulmonary valve prostheses for tricuspid valve-in-valve implantation (TVIV) within dysfunctional surgical tricuspid valve (TV) bioprostheses has been described in small reports.

11 marzo 2016

CIRCULATION. Interventional Cardiology. Changes in Arterial Access Site and Association With Mortality in the United Kingdom. Observations From a National Percutaneous Coronary Intervention Database

Mamas A. Mamas, BM BCh, DPhil; James Nolan, MD; Mark A. de Belder, MD; Azfar Zaman, MD; Tim Kinnaird, MD; Nick Curzen, BM, PhD; Chun Shing Kwok, MBBS, MSc, BSc; Iain Buchan, MD; Peter Ludman, MD; Evangelos Kontopantelis, PhD; on behalf of the British Cardiovascular Intervention Society (BCIS) and the National Institute for Clinical Outcomes Research (NICOR)

Background: The transradial access (TRA) site has become the default access site for percutaneous coronary intervention in the United Kingdom, with randomized trials and national registry data showing reductions in mortality associated with TRA use. This study evaluates regional changes in access site practice in England and Wales over time, examines whether changes in access site practice have been uniform nationally and across different patient subgroups, and provides national estimates for the potential number of lives saved or lost associated with regional differences in access site practice.

01 mayo 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. A comparison between two different definitions of contrast-induced acute kidney injury in patients with ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention

Marco Centola, Stefano Lucreziotti, Diego Salerno-Uriarte, Carlo Sponzilli, Giulia Ferrante, Roberta Acquaviva, Diego Castini, Marianna Spina, Federico Lombardi, Mario Cozzolino, Stefano Carugo

Background: Contrast-induced acute kidney injury (CI-AKI) is associated with significantly increased mortality after primary percutaneous coronary intervention (pPCI) for ST-segment elevation myocardial infarction (STEMI). The prognostic value of CI-AKI depends on the definitions used to define it. We compare the predictive accuracy of long-term mortality of two definitions of CI-AKI on consecutive patients undergoing pPCI for STEMI.

01 mayo 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Coronary surgery is superior to drug eluting stents in multivessel disease. Systematic review and meta-analysis of contemporary randomized controlled trials

Umberto Benedetto, Mario Gaudino1, Colin Ng, Giuseppe Biondi-Zoccai, Fabrizio D´Ascenzo, Giacomo Frati, Leonard N. Girardi, Gianni D. Angelini, David P. Taggart

Objective: Current randomized controlled trials (RCTs) comparing percutaneous coronary intervention with drug eluting stent (DES-PCI) with coronary artery bypass grafting (CABG) in multivessel disease are underpowered to detect a difference in hard clinical end-points such as mortality, myocardial infarction and stroke. We aimed to overcome this limitation by conducting a meta-analysis of contemporary RCTs.

01 mayo 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Prognostic value of new onset atrial fibrillation after transcatheter aortic valve implantation: A FRANCE 2 registry substudy

Akira Furuta, Nicolas Lellouche1,2, Gauthier Mouillet2, Tarvinder Dhanjal2, Martine Gilard2, Marc Laskar2, Helene Eltchaninoff2, Jean Fajadet2, Bernard Iung2, Patrick Donzeau-Gouge2, Pascal Leprince2, Alain Leuguerrier2, Alain Prat2, Jean-Luc Dubois-Rande2, Emmanuel Teiger2

Background: The development of new onset atrial fibrillation (NOAF) post-transcatheter aortic valve implantation (TAVI) is common and may be associated with an adverse prognosis. This study seeks to identify incidence, predictors, and impact of NOAF post-TAVI.

01 mayo 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Wound complications and surgical events in de novo heart transplant patients treated with everolimus: Post-hoc analysis of the SCHEDULE trial

Mitra Rashidi, Sorosh Esmaily, Arnt E. Fiane, Einar Gude, Kim A.Tønseth, Thor Ueland, Finn Gustafsson, Hans Eiskjær, Göran Rådegran, Göran Dellgren

Objectives: The use of mammalian target of rapamycin (mTOR) inhibitors have been limited by adverse events (AE), including delayed wound healing. We retrospectively reviewed all AE and serious AE (SAE) in The Scandinavian heart transplant (HTx) everolimus (EVE) de novo trial with early calcineurin (CNI) avoidance (SCHEDULE). The aim of the study was to compare wound complications between EVE and CNI based regimen.

15 mayo 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Provisional vs. two-stent technique for unprotected left main coronary artery disease after ten years follow up: A propensity matched analysis

Fabrizio D´Ascenzo, Mario Iannaccone, Francesca Giordana, Alaide Chieffo, Stephen O. Connor, L. Christian Napp, SujaySubash Chandran, José María de la Torre Hernández, Shao-Liang Chen, Ferdinando Varbella, Pierluigi Omedè, Salma Taha, Emanuele Meliga, Hiroyoshi Kawamoto, Antonio Montefusco, Mervyn Chong, Philippe Garot, Lin Sin, Valeria Gasparetto, Mohamed Abdirashid, Enrico Cerrato, Giuseppe Biondi-Zoccai, Fiorenzo Gaita, Javier Escaned, David Hiddick Smith, Thierry Lefèvre, Antonio Colombo, Imad Sheiban, Claudio Moretti

Aims: There is uncertainty on which stenting approach confers the best long-term outlook for unprotected left main (ULM) bifurcation disease.

15 mayo 2016

INTERNATIONAL JOURNAL OF CARDIOLOGY. Frequency and prognostic significance of access site and non-access site bleeding and impact of choice of antithrombin therapy in patients undergoing primary percutaneous coronary intervention. The EUROMAX trial

Sinem Kilic1, Arnoud W.J. van´t Hof, Jurrien ten Berg1, Ana Ayesta Lopez1, Uwe Zeymer1, Martial Hamon1, Louis Soulat1, Debra Bernstein1, Efthymios N. Deliargyris1, Phillippe Gabriel Steg1

Background: The overall impact of post percutaneous coronary intervention (PCI) bleeding on long term prognosis after acute coronary syndromes (ACS) has been established, but it may differ between access and non-access related bleeding events. The impact of antithrombin choice on bleeding may also differ according to the origin of the bleed. We sought to determine the origin of bleeding relative to the access site, its prognostic significance and the respective impact of antithrombin therapy in the EUROMAX trial.

01 mayo 2016

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. Aortic regurgitation following transcatheter aortic valve replacement: Impact of preprocedural left ventricular diastolic filling patterns on late clinical outcomes

Amir Halkin MD1,*, Arie Steinvil MD1, Galit Aviram MD2, Simon Biner MD1, Shmuel Banai MD1, Gad Keren MD1, Ariel Finkelstein1 andYan Topilsky MD1

Objectives: To investigate the impact of preprocedural left ventricular (LV) diastolic function on outcomes of patients with postprocedural aortic regurgitation (ARpost) following transcatheter aortic valve replacement (TAVR).

01 mayo 2016

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. Balloon-expandable transcatheter aortic valve replacement in patients with extreme aortic valve calcification

Yigal Abramowitz MD*, Hasan Jilaihawi MD, Tarun Chakravarty MD, Mohammad Kashif MD, George Matar BS, Babak Hariri MD, Jigar Patel MD, Mamoo Nakamura MD, Wen Cheng MD andRaj R. Makkar MD*

Objectives: To assess the procedural and short-term clinical outcome of performing balloon-expandable TAVR in patients with extremely calcified aortic valves.

01 mayo 2016

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. Sheathless guide catheter in transradial percutaneous coronary intervention for ST-segment elevation myocardial infarction

Masaki Miyasaka MD1,*, Norio Tada MD1, Shigeaki Kato PhD1, Masahiro Kami MD2, Kazunori Horie MD1, Taku Honda MD1, Kaname Takizawa MD1, Tatsushi Otomo MD1 andNaoto Inoue MD1

Objectives: The aim of this study was to assess the safety and efficacy of sheathless guide catheters in transradial percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI).

01 mayo 2016

CATHETERIZATION & CARDIOVASCULAR INTERVENTIONS. Percutaneous coronary intervention with the TandemHeart™ percutaneous left ventricular assist device support: Six years of experience and outcomes

Angelo Nascimbene MD1,2,3, Pranav Loyalka MD1,2,3, Igor D. Gregoric MD1,2,3 andBiswajit Kar MD1,2,3,*

Objectives: Our study was designed to evaluate the outcomes of TandemHeart™ assistance during percutaneous coronary intervention, specifically in relationship to pre-procedural clinical and hemodynamic risk factors in patients ineligible for surgical revascularization.