01 marzo 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Utilization and 1-Year Mortality for Transcatheter Aortic Valve Replacement and Surgical Aortic Valve Replacement in New York Patients With Aortic Stenosis. 2011 to 2012

Edward L. Hannan, PhDa; Zaza Samadashvili, MDa; Nicholas J. Stamato, MDb; Stephen J. Lahey, MDc; Andrew Wechsler, MDd; Desmond Jordan, MDe; Thoralf M. Sundt, III, MDf; Jeffrey P. Gold, MDg; Carlos E. Ruiz, MDh; Mohammed H. Ashraf, MDi; Craig R. Smith, MDe

Objectives: The purpose of this study was to investigate changes in the use of transcatheter aortic valve replacement (TAVR) relative to surgical aortic valve replacement (SAVR) and to examine relative 1-year TAVR and SAVR outcomes in 2011 to 2012 in a population-based setting.

01 marzo 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Changes in Coronary Blood Flow After Acute Myocardial Infarction. Insights From a Patient Study and an Experimental Porcine Model

Guus A. de Waard, MDa; Maurits R. Hollander, MDa; Paul F.A. Teunissen, MDa; Matthijs F. Jansen, MDa; Elise S. Eerenberg, MDb; Aernout M. Beek, MD, PhDa; Koen M. Marques, MD, PhDa; Peter M. van de Ven, PhDc; Ingrid M. Garrelds, MScd; A.H. Jan Danser, PhDd; Dirk J. Duncker, MD, PhDe; Niels van Royen, MD, PhDa

Objectives: The aim of this study was to determine the effects of an acute myocardial infarction (AMI) on baseline and hyperemic flow in both culprit and nonculprit arteries.

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Pre-Procedural Hemodynamic Status Improves the Discriminatory Value of the Aortic Regurgitation Index in Patients Undergoing Transcatheter Aortic Valve Replacement

Jan-Malte Sinning, MDa; Anja Stundl, MDa; Simon Pingel, MDa; Marcel Weber, MDa; Alexander Sedaghat, MDa; Christoph Hammerstingl, MDa; Mariuca Vasa-Nicotera, MDa; Fritz Mellert, MDb; Wolfgang Schiller, MDb; Jan Kovac, MDc,d; Armin Welz, MDb; Eberhard Grube, MDa; Nikos Werner, MDa; Georg Nickenig, MDa

Objectives: The aims of this study were to increase the discriminatory value of the aortic regurgitation index (ARI) for the assessment of paravalvular regurgitation (PVR) and to further elucidate the association between aortic regurgitation severity and mortality after transcatheter aortic valve replacement (TAVR).

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. The Spectrum of Cardiovascular Lesions Requiring Intervention in Adults After Kawasaki Disease

John B. Gordon, MDa; Lori B. Daniels, MDb; Andrew M. Kahn, MDb; Susan Jimenez-Fernandez, MDc; Matthew Vejar, BSc; Fujito Numano, MDc; Jane C. Burns, MDc

Objectives: The aim of this study was to characterize the range of management issues raised by adults with cardiovascular sequelae from Kawasaki disease (KD) in childhood.

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Safety and Efficacy of New-Generation Drug-Eluting Stents in Women Undergoing Complex Percutaneous Coronary Artery Revascularization. From the WIN-DES Collaborative Patient-Level Pooled Analysis

Gennaro Giustino, MDa; Usman Baber, MD, MSca; Melissa Aquino, MSca; Samantha Sartori, PhDa; Gregg W. Stone, MDb; Martin B. Leon, MDb; Philippe Genereux, MDc,d,e; George D. Dangas, MD, PhDa; Jaya Chandrasekhar, MBBSa; Takeshi Kimura, MDf; Olga Salianskia; Giulio G. Stefanini, MD, PhDg; P. Gabriel Steg, MD, PhDh; Stephan Windecker, MD, PhDi; William Wijns, MDj; Patrick W. Serruys, MD, PhDk; Marco Valgimigli, MD, PhDl; Marie-Claude Morice, MDm; Edoardo Camenzind, MDn; Giora Weisz, MDb,o; Pieter C. Smits, MDp; David E. Kandzari, MDq; Soren Galatius, MDr; Clemens Von Birgelen, MDs; Robert Saporitos; Raban V. Jeger, MDt; Ghada W. Mikhail, MDu; Dipti Itchhaporia, MDv; Laxmi Mehta, MDw; Rebecca Ortega, MHAx; Hyo-Soo Kim, MDy; Adnan Kastrati, MDz; Alaide Chieffo, MDaa; Roxana Mehran, MDa

Objectives: The purpose of this study was to investigate the safety and efficacy of new-generation drug-eluting stents (DES) versus early-generation DES in women undergoing complex percutaneous coronary intervention (CPCI).

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Radial Access Reduces Mortality in Patients With Acute Coronary Syndromes. Results From an Updated Trial Sequential Analysis of Randomized Trials

Giuseppe Andò, MD, PhDa; Davide Capodanno, MD, PhDb

Objectives: The authors sought to investigate whether the cumulative evidence coming from randomized studies has reached the necessary power to consider radial access as a bleeding avoidance strategy that reduces mortality and ischemic endpoints in patients with acute coronary syndromes (ACS).

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Effect of Pre-Hospital Ticagrelor During the First 24 h After Primary Percutaneous Coronary Intervention in Patients With ST-Segment Elevation Myocardial Infarction. The ATLANTIC-H24 Analysis

Gilles Montalescot, MD, PhDa; Arnoud W. van ’t Hof, MD, PhDb; Leonardo Bolognese, MDc; Warren J. Cantor, MDd; Angel Cequier, MD, PhDe; Mohamed Chettibi, MD, PhDf; Jean-Philippe Collet, MD, PhDa; Shaun G. Goodman, MDg; Christopher J. Hammett, MB, ChBh; Kurt Huber, MDi; Magnus Janzon, MD, PhDj; Frédéric Lapostolle, MD, PhDk; Jens Flensted Lassen, MD, PhDl; Muriel Licour, MScm; Béla Merkely, MD, PhDn; Néjoua Salhi, MDo; Johanne Silvain, MD, PhDa; Robert F. Storey, MD, DMp; Jurriën M. ten Berg, MD, PhDq; Anne Tsatsaris, MDm; Uwe Zeymer, MDr; Eric Vicaut, MD, PhDs; Christian W. Hamm, MD, PhDt

Objectives: The aim of this landmark exploratory analysis, ATLANTIC-H24, was to evaluate the effects of pre-hospital ticagrelor during the first 24 h after primary percutaneous coronary intervention (PCI) in the ATLANTIC (Administration of Ticagrelor in the cath Lab or in the Ambulance for New ST elevation myocardial infarction to open the Coronary artery) study.

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Vasomotor Function Comparative Assessment at 1 and 2 Years Following Implantation of the Absorb Everolimus-Eluting Bioresorbable Vascular Scaffold and the Xience V Everolimus-Eluting Metallic Stent in Porcine Coronary Arteries. Insights From In Vivo Angiography, Ex Vivo Assessment, and Gene Analysis at the Stented/Scaffolded Segments and the Proximal and Distal Edges

Bill D. Gogas, MD, PhDa,b; James J. Benham, BSc; Steve Hsu, PhDc; Alexander Sheehy, MSc; David J. Lefer, PhDd; Traci T. Goodchild, PhDd; David J. Polhemus, BAd; Yasir H. Bouchi, BSb; Olivia Y. Hung, MD, PhDa,b; Sang-Yong Yoo, MD, PhDa,b,e; Udit Joshi, MDb; Don P. Giddens, PhDb,f; Alessandro Veneziani, PhDb,g; Arshed Quyyumi, MDh; Richard Rapoza, PhDc; Spencer B. King, III, MDa,b,i; Habib Samady, MDa,b

Objectives: The purpose of this study was to assess and compare in vivo the restoration of vasomotor function following Absorb bioresorbable vascular scaffold (BVS) (Abbott Vascular, Santa Clara, California) and metallic Xience V (XV) (Abbott Vascular, Santa Clara, California) stent implantations in porcine coronary arteries at 1 and 2 years.

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Bioresorption and Vessel Wall Integration of a Fully Bioresorbable Polymeric Everolimus-Eluting Scaffold. Optical Coherence Tomography, Intravascular Ultrasound, and Histological Study in a Porcine Model With 4-Year Follow-Up

Shimpei Nakatani, MDa; Yuki Ishibashi, MD, PhDa; Yohei Sotomi, MDb; Laura Perkins, DVM, PhDc; Jeroen Eggermont, PhDd; Maik J. Grundeken, MDb; Jouke Dijkstra, PhDd; Richard Rapoza, PhDc; Renu Virmani, MDe; Patrick W. Serruys, MD, PhDf; Yoshinobu Onuma, MD, PhDa

Objectives: The aim of the present study was to investigate the relationship between the integration process and luminal enlargement with the support of light intensity (LI) analysis on optical coherence tomography (OCT), echogenicity analysis on intravascular ultrasound, and histology up to 4 years in a porcine model.

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Bicuspid Aortic Valve Stenosis. Favorable Early Outcomes With a Next-Generation Transcatheter Heart Valve in a Multicenter Study

Gidon Y. Perlman, MDa; Philipp Blanke, MDa; Danny Dvir, MDa; Gregor Pache, MDb; Thomas Modine, MDc; Marco Barbanti, MDd; Erik W. Holy, MDe; Hendrik Treede, MDf; Philipp Ruile, MDb; Franz-Josef Neumann, MDb; Caterina Gandolfo, MDg; Francesco Saia, MDh; Corrado Tamburino, MDd; George Mak, MDa; Christopher Thompson, MDa; David Wood, MDa; Jonathon Leipsic, MDa; John G. Webb, MDa

Objectives: This study evaluated the results of transcatheter aortic valve replacement (TAVR) in bicuspid aortic stenosis (AS) using a new-generation TAVR device.

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Changes in the Pacemaker Rate After Transition From Edwards SAPIEN XT to SAPIEN 3 Transcatheter Aortic Valve Implantation. The Critical Role of Valve Implantation Height

Fernando De Torres-Alba, MD; Gerrit Kaleschke, MD; Gerhard Paul Diller, MD, PhD; Julia Vormbrock, MD; Stefan Orwat, MD; Robert Radke, MD; Florian Reinke, MD; Dieter Fischer, MD; Holger Reinecke, MD; Helmut Baumgartner, MD

Objectives: The aim of this study was to analyze the pacemaker implantation rate (PMIR) with the new balloon-expandable Edwards SAPIEN 3 valve (S3) and the factors associated with it.

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Combination of the Thermodilution-Derived Index of Microcirculatory Resistance and Coronary Flow Reserve Is Highly Predictive of Microvascular Obstruction on Cardiac Magnetic Resonance Imaging After ST-Segment Elevation Myocardial Infarction

Sung Gyun Ahn, MD, PhDa,b; Olivia Y. Hung, MD, PhDb; Jun-Won Lee, MDa; Ji Hyun Lee, MDa; Young Jin Youn, MDa; Min-Soo Ahn, MDa; Jang-Young Kim, MD, PhDa; Byung-Su Yoo, MD, PhDa; Seung-Hwan Lee, MD, PhDa; Junghan Yoon, MD, PhDa; Woocheol Kwon, MD, PhDc; Habib Samady, MDa

Objectives: The aim of this study was to investigate the predictive accuracy of invasive coronary microvascular indexes for identifying microvascular obstruction (MVO) on cardiac magnetic resonance imaging (CMR) in patients treated with primary percutaneous coronary intervention (PCI) for ST-segment elevation myocardial infarction (STEMI).

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Randomized Trial of Polymer-Free Sirolimus- and Probucol-Eluting Stents Versus Durable Polymer Zotarolimus-Eluting Stents. 5-Year Results of the ISAR-TEST-5 Trial

Sebastian Kufner, MDa; Jonas Sorgesa; Julinda Mehilli, MDb,c; Salvatore Cassese, MD, PhDa; Janika Repp, MDa; Jens Wiebe, MDa; Raphaela Lohaus, MDa; Annalena Lahmann, MDa; Tobias Rheude, MDa; Tareq Ibrahim, MDd; Steffen Massberg, MDb,c; Karl L. Laugwitz, MDc,d; Adnan Kastrati, MDa,c; Robert A. Byrne, MB, BCh, PhDa

Objectives: The aim of this study was to evaluate the late clinical performance of a polymer-free sirolimus- and probucol-eluting stent compared with a new-generation durable polymer-based zotarolimus-eluting stent.

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. The Impact of Bleeding Avoidance Strategies on Hospital-Level Variation in Bleeding Rates Following Percutaneous Coronary Intervention. Insights From the National Cardiovascular Data Registry CathPCI Registry

Amit N. Vora, MD, MPHa; Eric D. Peterson, MD, MPHa; Lisa A. McCoy, MSa; Kirk N. Garratt, MDb; Michael A. Kutcher, MDc; Steven P. Marso, MDd; Matthew T. Roe, MD, MHSa; John C. Messenger, MDe; Sunil V. Rao, MDa

Objectives: The aim of this study was to explore whether the use of bleeding avoidance strategies (BAS) explains variability in hospital-level bleeding following percutaneous coronary intervention.

01 abril 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Continuum of Vasodilator Stress From Rest to Contrast Medium to Adenosine Hyperemia for Fractional Flow Reserve Assessment

Nils P. Johnson, MD, MSa; Allen Jeremias, MD, MScb,c; Frederik M. Zimmermann, MDd; Julien Adjedj, MDe; Nils Witt, MD, PhDf; Barry Hennigan, MB BCh BAO, BMedScig,h; Bon-Kwon Koo, MD, PhDi; Akiko Maehara, MDc,j; Mitsuaki Matsumura, BSc; Emanuele Barbato, MD, PhDe,k; Giovanni Esposito, MD, PhDk; Bruno Trimarco, MDk; Gilles Rioufol, MD, PhDl; Seung-Jung Park, MD, PhDm; Hyoung-Mo Yang, MD, PhDn,o; Sérgio B. Baptista, MDp; George S. Chrysant, MDq; Antonio M. Leone, MD, PhDr; Colin Berry, MBChB, PhDg,h; Bernard De Bruyne, MD, PhDe; K. Lance Gould, MDa; Richard L. Kirkeeide, PhDa; Keith G. Oldroyd, MBChB, MDg; Nico H.J. Pijls, MD, PhDd,s; William F. Fearon, MDn

Objectives: This study compared the diagnostic performance with adenosine-derived fractional flow reserve (FFR) ≤0.8 of contrast-based FFR (cFFR), resting distal pressure (Pd)/aortic pressure (Pa), and the instantaneous wave-free ratio (iFR).