01 septiembre 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Structural Damage of Jailed Guidewire During the Treatment of Coronary Bifurcation Lesions. A Microscopic Randomized Trial

Manuel Pan, MD; Soledad Ojeda, MD; Elena Villanueva, MD; Jorge Chavarria, MD; Miguel Romero, MD; Javier Suarez de Lezo, MD; Francisco Mazuelos, MD; Jose Segura, MD; Francisco Carrasco, MD; Francisco Hidalgo, MD; Jose Lopez Aguilera, MD; Sara Rodriguez, MD; Miguel Puente, MD; Jose Suarez de Lezo, MD

Objectives: The study sought to compare the safety (resistance to damage) and efficacy (ability to cross the side branch) of polymer-coated and non–polymer-coated guidewires in the jailed wire technique used during the percutaneous treatment of bifurcation lesions.

01 septiembre 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Percutaneous Intervention to Treat Platypnea–Orthodeoxia Syndrome. The Toronto Experience

Ashish H. Shah, MD, MD-Researcha; Mark Osten, MDa; Andrew Leventhal, MD, PhDa; Yvonne Bach, BScHa; Daniel Yoo, BScHa; Danny Mansour, BScHa; Lee Benson, MDb; William M. Wilson, MDa; Eric Horlick, MDCMa

Objectives: This study reviewed a series of patients treated with transcatheter closure of septal defect to treat platypnea-orthodeoxia syndrome, with specific attention to septal characteristics and device choice.

01 septiembre 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Contemporary Approach to Coronary Bifurcation Lesion Treatment

Fadi J. Sawaya, MDa; Thierry Lefèvre, MDa; Bernard Chevalier, MDa; Phillipe Garot, MDa; Thomas Hovasse, MDa; Marie-Claude Morice, MDa; Tanveer Rab, MDb; Yves Louvard, MDa

Abstract: Coronary bifurcations are frequent and account for approximately 20% of all percutaneous coronary interventions. Nonetheless, they remain one of the most challenging lesion subsets in interventional cardiology in terms of a lower procedural success rate and increased rates of long-term adverse cardiac events. Provisional side branch stenting should be the default approach in the majority of cases and we propose easily applicable and reproducible stepwise techniques associated with low risk of failure and complications.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Combined Use of Bivalirudin and Radial Access in Acute Coronary Syndromes Is Not Superior to the Use of Either One Separately. Meta-Analysis of Randomized Controlled Trials

George S. Mina, MD; George F. Gobrial, MD; Kalgi Modi, MD; Paari Dominic, MD

Objectives: The aim of this meta-analysis was to study the relation between access site and bivalirudin use on outcomes in patients with acute coronary syndrome (ACS).

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Prognostic Impact of Chronic Total Occlusions. A Report From SCAAR (Swedish Coronary Angiography and Angioplasty Registry)

Truls Råmunddal, MD, PhDa; Loes P. Hoebers, MDb; José P.S. Henriques, MD, PhDb; Christian Dworeck, MDa; Oskar Angerås, MD, PhDa; Jacob Odenstedt, MD, PhDa; Dan Ioanes, MDa; Göran Olivecrona, MD, PhDc; Jan Harnek, MD, PhDc; Ulf Jensen, MD, PhDd; Mikael Aasa, MD, PhDd; Per Albertsson, MD, PhDa; Hans Wedel, PhDe; Elmir Omerovic, MD, PhDa

Objectives: The aim of this study was to determine the prognostic impact of chronic total occlusion (CTO) on long-term mortality in a large prospective cohort.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Physiological Severity of Coronary Artery Stenosis Depends on the Amount of Myocardial Mass Subtended by the Coronary Artery

Hyung Yoon Kim, MDa; Hong-Seok Lim, MD, PhDb; Joon-Hyung Doh, MD, PhDc; Chang-Wook Nam, MD, PhDd; Eun-Seok Shin, MD, PhDe; Bon-Kwon Koo, MD, PhDf; Myeong-Ho Yoon, MD, PhDb; Seung-Jea Tahk, MD, PhDb; Doo Kyoung Kang, MD, PhDg; Young Bin Song, MD, PhDa; Joo-Yong Hahn, MD, PhDa; Seung Hyuk Choi, MD, PhDa; Hyeon-Cheol Gwon, MD, PhDa; Sang-Hoon Lee, MD, PhDa; Eun-Kyoung Kim, MDa; Sung Mok Kim, MD, PhDh; Yeonhyeon Choe, MD, PhDh; Jin-Ho Choi, MD, PhDa,i

Objectives: This study investigated the role of fractional myocardial mass (FMM), a vessel-specific myocardial mass, in the evaluation of physiological severity of stenosis. Using computed tomography angiography, the study investigated fractional myocardial mass, a concept of myocardial mass subtended by specific vessel, which could reduce anatomical-physiological mismatch.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Individual Long-Term Mortality Prediction Following Either Coronary Stenting or Bypass Surgery in Patients With Multivessel and/or Unprotected Left Main Disease. An External Validation of the SYNTAX Score II Model in the 1,480 Patients of the BEST and PRECOMBAT Randomized Controlled Trials

Yohei Sotomi, MDa; Rafael Cavalcante, MD, PhDb; David van Klaveren, MScc; Jung-Min Ahn, MDd; Cheol Whan Lee, MDd; Robbert J. de Winter, MD, PhDa; Joanna J. Wykrzykowska, MD, PhDa; Yoshinobu Onuma, MD, PhDb; Ewout W. Steyerberg, PhDc; Seung-Jung Park, MD, PhDd; Patrick W. Serruys, MD, PhDe

Objectives: The study sought to validate the SYNTAX (Synergy Between Percutaneous Coronary Intervention With Taxus and Cardiac Surgery) score II mortality prediction model after percutaneous coronary intervention (PCI) or coronary artery bypass grafting in a large pooled population of patients with multivessel coronary disease (MVD) and/or unprotected left main disease (UPLMD) enrolled in the PRECOMBAT (Bypass Surgery Versus Angioplasty Using Sirolimus-Eluting Stent in Patients With Left Main Coronary Artery Disease) and BEST (Artery Bypass Surgery and Everolimus-Eluting Stent Implantation in the Treatment of Patients with Multivessel Coronary Artery Disease) randomized controlled trials.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. The RENEW Trial. Efficacy and Safety of Intramyocardial Autologous CD34+ Cell Administration in Patients With Refractory Angina

Thomas J. Povsic, MD, PhDa; Timothy D. Henry, MDb; Jay H. Traverse, MDc; F. David Fortuind; Gary L. Schaer, MDe; Dean J. Kereiakes, MDf; Richard A. Schatz, MDg; Andreas M. Zeiher, MDh; Christopher J. White, MDi; Duncan J. Stewart, MDj; E. Marc Jolicoeur, MDk; Theodore Bass, MDl; David A. Henderson, MDm; Patricia Dignacco, BSMTa; Ziangoiong Gu, MSa; Hussein R. Al-Khalidi, PhDa; Candice Junge, PhDn; Adel Nada, MD, MS, MFPMo; Andrea S. Hunt, MBAp; Douglas W. Losordo, MDq

Objectives: This study tested whether intramyocardial (IM) administration of mobilized, purified autologous CD34+ cells would improve total exercise time (TET) and angina frequency in patients with refractory angina.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Acute and 30-Day Outcomes in Women After TAVR. Results From the WIN-TAVI (Women´s INternational Transcatheter Aortic Valve Implantation) Real-World Registry

Alaide Chieffo, MDa; Anna Sonia Petronio, MDb; Julinda Mehilli, MDc; Jaya Chandrasekhar, MBBSd; Samantha Sartori, PhDd; Thierry Lefèvre, MDe; Patrizia Presbitero, MDf; Piera Capranzano, MDg; Didier Tchetche, MDh; Alessandro Iadanza, MDi; Gennaro Sardella, MDj; Nicolas M. Van Mieghem, MD, PhDk; Emanuele Meliga, MDl; Nicholas Dumonteil, MDm; Chiara Fraccaro, MD, PhDn; Daniela Trabattoni, MDo; Ghada W. Mikhail, MDp; Samin Sharma, MDq; Maria Cruz Ferrer, MDr; Christoph Naber, MDs; Peter Kievit, MDt; Michela Faggioni, MDb,d; Clayton Snyder, BScd; Marie Claude Morice, MDe; Roxana Mehran, MDd

Objectives: The study sought to examine the safety and performance of transcatheter aortic valve replacement (TAVR) using an all-female registry and to further explore the potential impact of female sex-specific characteristics on clinical outcomes after TAVR.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Mitral Regurgitation After Transcatheter Aortic Valve Replacement. Prognosis, Imaging Predictors, and Potential Management. CME

Carlos Cortés, MDa; Ignacio J. Amat-Santos, MD, PhDa; Luis Nombela-Franco, MDb; Antonio J. Muñoz-Garcia, MDc; Enrique Gutiérrez-Ibanes, MDd; José M. De La Torre Hernandez, MD, PhDe; Juan G. Córdoba-Soriano, MDf; Pilar Jimenez-Quevedo, MDb; José M. Hernández-García, MD, PhDc; Ana Gonzalez-Mansilla, MDd; Javier Ruano, MD, PhDe; Jesús Jimenez-Mazuecos, MD, PhDf; Javier Castrodeza, MDa; Javier Tobar, MDa; Fabian Islas, MDb; Ana Revilla, MDa; Rishi Puri, MBBS, PhDg; Ana Puerto, MSca; Itziar Gómez, MSca; Josep Rodés-Cabau, MD, PhDg; José A. San Román, MD, PhDa

Objectives: This study sought to analyze the clinical impact of the degree and improvement of mitral regurgitation in TAVR recipients, validate the main imaging determinants of this improvement, and assess the potential candidates for double valve repair with percutaneous techniques.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Valve Type, Size, and Deployment Location Affect Hemodynamics in an In Vitro Valve-in-Valve Model

Prem A. Midha, MSa; Vrishank Raghav, PhDa; Jose F. Condado, MD, MSb; Ikechukwu U. Okafor, BSa; Stamatios Lerakis, MDb; Vinod H. Thourani, MDb; Vasilis Babaliaros, MDb; Ajit P. Yoganathan, PhDa

Objectives: The purpose of this study was to optimize hemodynamic performance of valve-in-valve (VIV) according to transcatheter heart valve (THV) type (balloon vs. self-expandable), size, and deployment positions in an in vitro model.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Successful Treatment of Compression of an Anomalous Circumflex Artery After Aortic Valve Replacement With Percutaneous Coronary Intervention

Marta López Castillo, MD; Roberto Martín Reyes, MD; Julia Palfy, MD; Juan Antonio Franco, MD, PhD; Antonio Piñero, MD; Felipe Navarro, MD; Marta Tomás, MD; Gonzalo Aldámiz, MD; Jerónimo Farré, MD, PhD

A 74-year-old woman was admitted to the intensive care unit with acute pulmonary edema requiring endotracheal intubation. The presence of an unknown critical aortic stenosis was revealed with markedly calcified mitral annulus and preserved left ventricular ejection fraction. Because the patient presented rapid clinical deterioration, urgent surgical aortic valve replacement (AVR) with a biological prosthesis was carried out without performing a coronary anatomy study, because of the hemodynamic instability of the patient.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Intravascular Ultrasound-Diagnosed Acute Aortic Dissection Involving Left Main Closure

Kayo Takahashi, MD; Shinji Inaba, MD; Kenji Kikuchi, RT; Hiroe Aisu, MD; Toru Morofuji, MD; Makoto Saito, MD; Takumi Sumimoto, MD

A 72-year-old man was admitted to our hospital presenting with cardiogenic shock following chest pain. Prehospital 12-lead electrocardiography showed lead aVR ST-segment elevation with widespread ST-segment depression, suggesting acute left main (LM) obstruction. Therefore, we decided to perform coronary angiography immediately after admission for release from broad myocardial ischemia.

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Predictors, Trends, and Outcomes (Among Older Patients ≥65 Years of Age) Associated With Beta-Blocker Use in Patients With Stable Angina Undergoing Elective Percutaneous Coronary Intervention. Insights From the NCDR Registry

Apurva A. Motivala, MDa; Valay Parikh, MDb; Matthew Roe, MD, MHSc; David Dai, PhDc; J. Dawn Abbott, MDd; Abhiram Prasad, MDe,f; Debabrata Mukherjee, MD, MSg

Objectives: This study sought to examine predictors, trends, and outcomes associated with β-blocker prescriptions at discharge in patients with stable angina without prior history of myocardial infarction (MI) or systolic heart failure (HF) undergoing elective percutaneous coronary intervention (PCI).

01 agosto 2016

JACC: CARDIOVASCULAR INTERVENTIONS. Mid- to Long-Term Clinical Outcomes of Patients Treated With the Everolimus-Eluting Bioresorbable Vascular Scaffold. The BVS Expand Registry

Cordula M. Felix, MD; Jiang Ming Fam, MD; Roberto Diletti, MD, PhD; Yuki Ishibashi, MD, PhD; Antonios Karanasos, MD, PhD; Bert R.C. Everaert, MD, PhD; Nicolas M.D.A. van Mieghem, MD, PhD; Joost Daemen, MD, PhD; Peter P.T. de Jaegere, MD, PhD; Felix Zijlstra, MD, PhD; Evelyn S. Regar, MD, PhD; Yoshinobu Onuma, MD, PhD; Robert-Jan M. van Geuns, MD, PhD

Objectives: This study sought to report on clinical outcomes beyond 1 year of the BVS Expand registry